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The blisters break, leaving tender ulcers (sores) that may take two to four weeks to heal the first time they occur.

Typically, another outbreak can appear weeks or months after the first, but it almost always is less severe and shorter than the first outbreak.

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Transmission can occur from an infected partner who does not have a visible sore and may not know that he or she is infected.

HSV-1 can cause genital herpes, but it more commonly causes infections of the mouth and lips, so-called ? HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection.

Between the late 1970s and the early 1990s, the number of Americans with genital herpes infection increased 30 percent.

Genital HSV-2 infection is more common in women (approximately one out of four women) than in men (almost one out of five).

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